What makes a systematic review "living"?
Here, we explain the concept of LSR and why EGRAPA is engaged in this.
A living review is continually updated in a predetermined period, incorporating relevant new evidence as it becomes available, and is particularly important in fields where research evidence is emerging rapidly, current evidence is uncertain, and new research may change policy or practice decisions (Elliott et al., 2017).
EGRAPA promotes research work aiming to develop and sustain an international knowledge community about physical exercise at an older age.
Here, we will collect and provide data of our LSRs, which deals with myokines and physical activity.
The Myokines living systematic review:
Last updated: 3rd of March 2025
More information regarding the protocol can be found in the International Prospective Register of Systematic Reviews (PROSPERO) database (registration number CRD42023416996) and in the published protocol paper:
Vints, W. A. J. et al. Myokines as mediators of exercise-induced cognitive changes in older adults: protocol for a comprehensive living systematic review and meta-analysis. Front. Aging Neurosci. 15, 1213057 (2023).
Last search: 15th of May 2025
Last completed article screening: 1st of November 2024
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43 studies (41 chronic exercise studies and 2 acute exercise studies) were eligible for inclusion and included in the published article: (doi number will be added upon publication).
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Eligible articles, not yet incorporated in a published article: 0
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Details of the eligible articles:
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Not Applicable
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Articles that underwent full text screening, but were not eligible with exclusion reasons:
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Not Applicable
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Decisions regarding integration of new evidence:
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03-03-2025:
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To be integrated later: 0 articles
Justification of delayed incorporation: No new evidence is retrieved that alters the main conclusions of the article in a way that the authors deem it necessary to publish an updated version.